Why are some people in some countries so much healthier than others? This course will explore the factors that explain the unequal distribution of health and disease in the world. The course will begin with an introduction to the language of global health: the burden of disease, epidemiology, cost-effectiveness, and health systems. It will then analyze the rationale for and modes of intervention to improve global health by exploring a number of high-profile topics, including the HIV/AIDS epidemic, access to pharmaceuticals, human resources for health, and maternal and child health. The course will incorporate knowledge and views from multiple academic disciplines (public health, economics, politics, management, sociology, etc) and does not require any background knowledge. It is open to students in all degree concentrations.